子宫内膜菌群检测 Emma

EMMA
Benefits
Indications

What is the EMMA test?

EMMA is a test that analyzes the endometrial microbiome for a better reproductive prognosis.

It indicates the endometrial microbiome balance, providing information on the proportions of healthy endometrial bacteria, including those linked to higher pregnancy rates.

What is the procedure?

Why use EMMA test?

EMMA uses the latest Next Generation Sequencing (NGS) technology to provide microbiome information in endometrial tissue by analyzing the complete endometrial microbiome profile.
EMMA can determine the percentage of Lactobacillus present in the endometrium, to improve the patient’s reproductive prognosis.
EMMA indicates the possible presence of bacterial pathogens that can cause chronic endometritis or other diseases.
If the endometrium is non-Lactobacillus dominated, the report will suggest the adequate treatment for each patient.
EMMA will determine whether the uterine microbial environment is optimal or not for embryo implantation.
This test can be performed in a small piece of endometrial tissue.

Who should use the EMMA test?

Patients with repeated implantation failure (RIF)
EMMA can be beneficial for any patient wishing to conceive, by assessing the microbiological environment that the embryo will encounter at implantation.

Test Limitations

These tests are not able to detect resistance to antibiotics.
Detects the presence of pathogens associated with chronic endometritis. A negative result does not rule out the presence of other endometrial pathogens.
The tests are not 100% accurate at determining the bacterial species.

Documentation

EMMA Specialists' documents

Technical Sheets

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Brochure

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Scientific evidence

Relevant related studies:

Evidence that the endometrial microbiota has an effect on implantation success or failure. Moreno, Inmaculada et al. American Journal of Obstetrics & Gynecology, Volume 215, Issue 6, 684 – 703.

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Human Microbiome Project Consortium. Structure, function and diversity of the healthy human microbiome. Nature 2012; 486:207–14.

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Human Microbiome Project Consortium. Structure, function and diversity of the healthy human microbiome. Nature 2012; 486:207–14

Moreno I, Codoñer FM, Vilella F, Valbuena D, Martinez-Blanch JF, Jimenez-Almazan J, Alonso R, Alama P, Remohi J, Pellicer A, Ramon D, Simon C. Evidence that the endometrial microbiota has an effect on implantation success or failure. Am J Obstet Gynecol. 2016; 215:684-703.